Welcome to an introduction on organic chemistry for people with salicylate sensitivity. This lesson will teach you basics between inorganic chemistry (NaCl salt, H20 water) and organic chemistry (benzene rings, phenols, and salicylates).

Thanks so much for watching. Here are some screenshots of what is in the video.

Agenda:

• Intro - learn what a salicylate is based on shape using ChemSpider 0:00
• What is organic chemistry 3:13
• What is inorganic chemistry 12:23
• What is an aromatic 16:00
• What is a benzene, phenol, and salicylate 20:05
• Different salicylate molecules 21:43
• Bound vs unbound salicylates 24:54
• Test what you've learned (examples) 28:57

Slides

The following are slides that are shown in the video. Please watch the video (captioning and transcript available through YouTube)

Organic Chemistry relies on covalent bonding and includes a "carbon backbone" in most cases. Organic does not mean natural, healthy, or free of chemicals.

Above are four examples of organic chemicals including a portion of Chlorophyll B, Methanol, Octanol, and Monounsaturated fat.

There are many ways to symbolized compounds in organic chemistry. It can be listed as a formula with letters and numbers, but this doesn't tell you anything about shape and structure. If you search for a compound, you can often find a 3D shape of a molecule. Letters and lines are the most common, and often tells us so much right away. Hydrogens are often assumed and don't need to be written out. We make the assumption that Carbon can form four bonds, Hydrogens can only make one. If it appears a carbon is missing a bond or two, we can assume a hydrogen is in each spot.

One single line means there's a single bond. These are easier to break than double or triple bonds. Double bonds are with two lines, Triple with three lines (although quite uncommon).

A minus sign, means that there is the capacity for another bond, but it is missing one. This usually means it can hook up with a hydrogen or another chemical.

In the case of the lower right image/scribble - there is a benzene ring- hexagon with three double bonds. This can also be written as a hexagon with a circle inside - faster to write. This molecule is a benzene and has 6 Carbons and 6 Hydrogens (not shown, but implied)

The OH group cirlcled is an alcohol group.

Inorganic chemistry covers all of the other chemicals (organic features carbon, there's still carbon in this world, but not as much) and they use ionic bonding. Chemicals are attracted to one another by having a positive or negative charge (kind of like magnets) and come together.  This lesson assumes - if it's inorganic, then it's not a salicylate. Table salt, Potassium chloride, sulfate, sulfite, ozone, water, barium sulfite, barium sulfate, iron oxides and many more are not salicylates. One place to start is that they don't have carbon, and they use ionic bonding. You can check ChemSpider for the molecular structure and information about the chemical if you're not sure where to start. PubChem is another one. I like to check both, and they sometimes have different information.

Aromatics were first named because the early chemicals we knew about in this group were smelly, but that has changed, so the term has now been broadened out. Aromatics no longer mean odorous in the chemical world and are strictly used for carbon circles with covalent bonding that meet certain criteria. We won't go into that here, but the above images show three different examples of aromatics. Salicylic acid is an example of an odorless aromatic. You can check out the profile on PubChem and search for odor within the page.

Functional groups are shapes/chemicals that group together and attach to a carbon or molecule group.

• OH is an alcohol group (usually adds -ol or -nol to a molecular name)
• COOH is a carbocylic acid, or just called acid sometimes.
• N(H,R)2 is an amine - not going into that, but thought some people might find that helpful.

This is the progression from benzene ring to salicylate. A phenol is a benzene ring with an alcohol group. A Salicylate has the acid group (this one is missing a hydrogen) and the phenol on there.

All salicylates have a phenol or benzene, but not all benzenes are salicylates, and not all phenols are salicylates. Some benzenes and phenols comprise needed chemicals in our body and are safe.

Here are some examples of different salicylates. You can see that for the most part, there's a partial phenol and a partial carboxylic acid group in both examples. Also the OH group and the COOH group are next to each other on the carbon ring - let's call it Carbon 1 and Carbon 2 - the next four carbons are left alone.

Items reviewed:

The rest of the video covers several examples of molecules and why they are or are not a salicylate. Some are a little too close for me to make a call, so I explain why that is.

• Nitrates/Nitrites
• Oxalates
• Citric acid and Ascorbic acid
• Magnesium stearate/Calcium stearate
• Dopamine/Adrenalines
• Benzoates/Benzoic acid
• Dyes: Manganese Violet C188842, Iron (III) oxide, Iron (II) oxide, and Curcumin (Tumeric)

Thanks for learning along with me!

Sarah

Transcript

Provided for visual learners, improved accessibility, and for translating the page

[00:00]

Hello, welcome to Low-Sal-Life. I am so glad you guys decided to click on the title because obviously, it is basically not for the faint of heart. But we're going to make it easy today, we're going to talk about basically an introduction of organic chemistry to that you as somebody who has allergies or salicylate sensitivity, will be able to look at basic chemicals and decide whether or not it's a risk for you based on it being a salicylate or not. So that's our goal today, I've got, we're going to do a little bit different format, I've got some slides that we'll be going through, and I'll be drawing on them just to be able to circle things for you. And I hope that this format works for you and that you're not bored. I don't think it's terribly boring. But you know, some people might think it's over their head, but really, I don't think it is, if you've ever put together Legos or puzzles, or, you know, sorted silverware in a drawer, you should be able to understand the concepts I'm going to teach you today. Special thanks to ChemSpider for having all of these items available to look at. My goal is that you could feel confident enough to go on PubChem or ChemSpider, those are my two favorite websites to look and be able to type in a chemical and be able to look at its shape and decide whether or not there is absolutely no risk, risk, or possible risk. So that's kind of how I kind of figure out like, what's what. So, here's the agenda that we're going to cover and I have the timestamps down below so you can easily go from one section to another. So, we're going to cover what is organic chemistry, what isn't organic chemistry, and then we'll be covering what an aromatic is. I think that that one it might be interesting for some people, then we'll cover what a benzene, phenol, and a salicylate is at its base its core, we'll look at different salicylate molecules. These might answer some of your questions when you're looking at the food lists to be able to understand it a little tiny bit better. We'll look at bound versus unbound salicylates, which a lot of people didn't realize was a thing, until I put my food list up and showed different results like Malakar and Kęszycka, for example, have different, they provide both a bound and unbound salicylate. So, we're going to just briefly cover what those are. But I will have a video in the future about that specifically. So, if you don't want to miss that, make sure you subscribe and hit that bell button. Because I may post in a week, I might post in a few months. So, make sure that you don't miss anything if you want to see when I post my next video, and then we'll have some examples and a little quiz at the end. So, let's get started. So just a reminder that chemistry covers all of the elements in the world and how they interact with each other. So just as a refresher, this is what a periodic table looks like. You can see that they are arranged in a certain order, this periodic table is conveniently colored. So, it makes it easier if you're trying to do some equations on your own. But we're not going to do that. I specifically want to look at organic compounds. I find organic chemistry interesting. I am not a chemist, I should say I am a biologist, but I you know organic chemistry actually required to get a biology degree, I think I would probably do a lot better now, especially since I'm a little bit more interested in it because of my salicylate sensitivity. But you know, the basics that we're going to cover today are going to be good. So, I do want to say that a lot of people use organic, most often related to food and as a positive trait. Organic doesn't mean that in the science world. So organic means basically having a carbon backbone or being made of carbons – it’s basically the backbone of life. We cannot exist without organic chemistry, our tissues and our bodies are made out of carbon atoms, and more so than any other element. So that's something to think about. I guess maybe water could be argued but organic does not imply healthy, even though we associated with life, it does not imply healthy, it actually, there are plenty of organic compounds that can harm you. And so, I will have some examples later. To the very basic definition, organic chemistry must require covalent bonding. And we're not going to go into that at all. But just know that there are two types of bonding, there's a covalent and another one, which we'll talk about in a moment, just so that we know that there's an, ionic bonding, couldn't remember it, just to know that there's at least those two types of bonds.

[05:36]

Here's an example of a couple of organic compounds. So, the one on the far left actually had to trim it off, because it was really long, but that's the main portion of chlorophyll B. This is the green energy store of plants. And you can see that it's a very complex molecule with lots of lines and shapes and N’s and O's. And that is an example of an organic compound. And that one you can eat. And it's probably good for you. The second one is methanol. And this is the small like, I think this is probably the smallest organic molecule, but it has one, one carbon in the center. And it's got the hydrogen bonds and an alcohol bond and OH bond attached to it. So that one only has one carbon, so not exactly a carbon backbone. But still, it uses covalent bonding. So that's why it's part of organic chemistry, you can go up to octanol. And that one, you can guess that oct- is eight. But if you wanted, you could count it 12345678 with an alcohol (OH) group at the end. So, I don't recommend consuming methanol or octanol, because those are poisonous, but they are also organic. So just kind of throwing that out there that this isn't just - organic is not good for us. Or natural, there are plenty of fossil fuel organic products. So just putting that out there. This last one is a monounsaturated fat, all of our fats are organic. And this one here you can see, we've got several carbons, 1234567 carbons on there, and then all the hydrogens are spelled out. You don't have to show all the hydrogens when you're looking at them. But this one here is very, they just broke it out for us so that we knew that there was at least hydrogens in there. Our next slide is going to be about symbolizing organic compounds. So, we could certainly do organic compounds in a formula. So that's one of the basic ways to talk about a chemical. One thing about formulas is that it doesn't give us any information about the shape. And that may or may not break a compound, as far as it being bio active or bio available in the body, or, you know, basically different shaped compounds can do different things. So, but if you want to know what the very basics are, the formula is a good place to start. Okay, so we'll stick with octanol, because that one's really simple. It doesn't have anything fancy on it, right? It's just a line with an OH group at the end. So, if we were going to write this as a formula, we would write it as C8 H18 O, meaning it has eight carbons, 18 hydrogen and one oxygen. So that would be how it's written as a formula. Here is a version of what it looks like as a 3D shape. Generally, every molecule, every element has a different color so that's helpful when you're looking at that. Here is an example of it written out with letters and lines. So, in this case, we're looking at every single, we've unpacked what we saw on the last slide, we've unpacked it and just showing every single element present and every bond. So here we have all of your carbons, you have your hydrogen and you have your oxygen. If we recall from the monounsaturated fat from the slide before, you can see that there is a double bond on here. So that is marked with two lines. A single bond has one line and then we can also not show the hydrogens that we can kind of count how many hydrogens there are, if once you get really good. So, you can just show it as a shape. So here every single corner that every little point, we can assume that there's a carbon at that point. And then we can also assume that they are hydrogens. So, the big thing with carbons is that they have the capacity to have four bonds.

[10:17]

So, in some cases, they'll have a double bond. But wherever there isn't a single or a double bond represented like in the line, we can assume that there is a hydrogen in its place. Here's an example of a salicylate and you can see that there are points on the hexagon, we can assume that there is a carbon there. So, you have six carbons in that little ring, you have some lines that are single, which imply a single bond, some lines are doubles, and those are double bonds. And then you have this the OH, so we can assume that the oxygen is the next point, not a carbon. And then on the other side, you can also see that there's a little minus sign. And that means that there is the ability to add a hydrogen or another bond, but in this case, where it's not represented. So that might mean that it could function freely as an ion, which we won't get into today. But basically, there is the capacity for an H there, or maybe attaching to another carbon, or something like that. And then just one other thing, when you see this hexagon, this is a benzene ring when it has those three double bonds inside. And it can also be represented, with just a circle in the middle. So, if you ever come across anything that just has a circle inside, it's just a faster way rather than being really precise and drawing in the double bonds. So that is the same symbol for a benzene ring. Alright, so now that we've talked about what organic chemistry is basically a carbon backbone, you have covalent bonding, and it can be represented by a lot of different symbols, but mostly lines. Next, we're going to talk about inorganic chemistry. And just very briefly, and basically, I want to cover that it is basically everything that is not organic chemistry. So, when you're looking at a periodic table, if you basically cross out carbon there, that's what the rest of inorganic chemistry covers, everything else. And there are some cases, I wrote a couple down here where there is carbon dioxide, CO2, carbonic acid, H2, CO3, those are carbon molecules. And so, they could be confused for organic chemistry, but they actually use ionic bonding and not covalent bonding. So that's the reason why they're in this camp and not the other one. Common items that you might come across that are also inorganic are sodium chloride NaCl. This is your basic table salt, sulphate SO4, so that Sulphur with four oxygens, or ozone, it's just three oxygens. So those are all types of inorganic chemistry. So, when somebody asks me, if, like we were looking at lipstick last week, and I mentioned that Barium sulphate is definitely not a salicylate, well, how can I be sure, and the reason why is because that is an inorganic compound, it doesn't contain carbon. And we can be really sure that that's not a salicylate. So here are some examples of inorganic compounds. The first is NaCl. It's basically just your plain table salt. Potassium chloride is like this to where you have one sodium molecule and one chlorine molecule. They get together through ionic bonding, they actually dissociate in water, so they kind of are free floating in water, but when they are dry, they become a solid and attached to one another. Calcium chloride isn't the one this is a calcium element with two chlorine elements. I believe calcium chloride is used in vitamins and supplements, I want to say and maybe some food preservatives. I do also want to say that just because it's inorganic, doesn't mean it's healthy. I'm just saying they're not salicylates. So, Mercury is on here. And so as lead we all know that those are detrimental to human health when consumed. So, this argument is not that everything on this periodic table is good for you. It is just an argument that they are not salicylates.

[15:13]

Okay. The last thing is the nitrates. Nitrites and nitrates are natural. And they could be synthetic food preservatives. They could be like, for example, they're in celery, naturally. Nitrate is just nitrogen with three oxygens. And this is what the shape looks like. Yeah, so there you go. Nitrates and nitrates, I can confidently say are not salicylates, they don't have any carbon, they don't have the shape of a salicylate, they don't use the same kind of bonding. Alright, we're going to move on. Okay, heading back to organic chemistry. Now that we know what is organic chemistry, we know what is not organic chemistry. Now we're going to go dive in a little bit more. Alright, in organic chemistry, there's something called an aromatic. Basically, this, I want to bring up first because it's the basic structure of a salicylate. But it also like organic means something casually or when related to money. But scientifically, it is rarely used correctly, right? Organic does not mean good for you, or natural. Aromatic does not have anything to do with odor or fragrance. As a matter of fact, there are plenty of aromatic compounds that have zero fragrance, aspirin is an example of one. So, let's look at a couple here, an aromatic. Also, we're not going to go into this, but there are certain criteria that go into this. But basically, we're looking at a carbon ring, it can be five carbons, it can be six carbons, I think I saw some that had a lot more. And an aromatic can contain all carbons only, or it can contain maybe some nitrogen or some oxygens in there. And I'm not going to go into this very much. But here are a couple of shapes. The first one is a simple aromatic, this one's called furan. And it's got four carbon atoms and an oxygen. So, a little bit different shape. Here, benzene, this is what we're going to focus on today. This one has six carbon atoms with three double bonds, this is called a benzene ring. Benzene is somewhat - it is aromatic in its pure form like this. So, it is we'll say odorous. The next one is a fused-ring. So basically, you have two benzenes attached to one another, but Naphthalene, this is to benzene rings attached. That is another example of an aromatic have fused rings together. Okay, another thing that we're going to talk about in organic chemistry is functional groups. So basically, you can have a base molecule, and they can change based on the functional group attached to it. So that's kind of where we're trying to get to, what is the base salicylate molecule and how does it change, because there's lots of different forms. And that's what makes it really hard, I want to talk about two that are really important. And the last one I thought you guys might like because I know a lot of you guys are amine sensitive. So, the first one is called an alcohol group. This is just an O-H group. This picture here that I drew shows the extra electrons that are available, basically, you can draw it with just an O H in the diagram. And that implies an alcohol group. The next one is a carboxylic acid group, and that's the C O O H, so we have the implied C in the middle. We've got the double bond to the O the oxygen above and then we have a single bond to the O with an H on there. So that's a C O O H, and that is basically an acid you know just you can call it an acid, but it's specifically carboxylic acid. And then the last one anytime you attach a nitrogen with a pair of electrons, you get an Amine. So here this is kind of funky how it's written but R stands for - it's basically like a variable, A stands for the rest of the chemical structure. So, you can put whatever you want in there as long as it has a nitrogen and a pair of electrons. That's what an Amine is.

[20:03]

All right, we're just about done with the lesson and then we're going to look at some examples. Next, we're going to look at the six carbon aromatics, specifically the benzene rings. These are interesting to us because they make the base of the salicylate. So, the first one, it should look familiar to you, you have the benzene ring, you've got six carbon atoms, you've got three double bonds, and you have implied hydrogens in there that aren't being shown. If we attach an alcohol group to this, it automatically becomes a phenol. So, some people in the food sensitivity world say that they're sensitive to phenols. I think that that's a little bit of a stretch, but it is broad enough that you're going to probably cover everything that you're sensitive to. I think it's a little bit too broad. But that is when people say they're phenol sensitive, that is what they're talking about. Okay, the last one is salicylates. So, you have your benzene, you basically have your phenol, right, you got your alcohol group attached to your benzene. And then you also have a carboxylic acid that's COO- attached here, COO- this one in particular, it says minus because they took the hydrogen off. So, this could essentially it makes it active. But there could be an H there too. So that's your carboxylic acid on there. And so we're going to move on to different salicylates in particular. So, this first one is salicylic acid. So, you've got your benzene ring, you've got your alcohol group on there that makes your phenol and then you have your carboxylic acid on the top of the COOH. This is what all the reports show on our food list. They report it in either in usually milligrams of salicylic acid per kilogram of food. And I didn't know that that one in particular is odorless. You can look on ChemSpider, and there should be attributes down below where it says whether or not it's fragrant or not. And then also whether or not has color. So that's something that can be helpful. For example, I was on a forum. And I noticed that somebody was really mad that their vitamin B's had yellow dye added and it wasn't in the ingredient list, and they would have never purchased it if it was had a dye with it. The reality is, is that B1 actually is yellow in color. So, if you want to double check that yourself, you could go to ChemSpider, pull up or PubChem, one of them, pull up the formula, the molecular formula. And then in the details, it should say if it's odorless, if there's an odor or if it has color and some of those chemical properties. So, that's super helpful. Alright, so here, you can see it, this is the same as the former Salicylate, except it now has the H represented meaning that it's a full carboxylic acid attached to it, the C O O H, and that's what gives the acid portion of the Salicylate. But essentially, you still have your base salicylate molecule there, here is acetyl salicylic acid, you can see that it's much more complex. But in this one, you still have the C O O H attached there on the right. And then on the left here, you have instead of an OH, you now have an O attached to a whole bunch of other stuff. So that's going to be the probably I'm guessing acetyl group, and this is aspirin. And then the last one is wintergreen oil. So, this one here you have your alcohol group there and then you have your COO group. And remember, I said that there was a minus sign earlier on the salicylate. So that means that there is a capacity for an H therefore, to make it a full carboxylic acid, a full COOH, but in this case, the H is replaced with another carbon. And then of course, there's going to be hydrogen off of those. And that one is very odorous wintergreen oil. Okay, the last thing we're going to talk about is bound versus unbound Salicylate and this is a really loaded question, especially since I've started posting the reports like Malakar and Kęszycka that they have tested both bound and unbound salicylate, this quote at the top was from Malakar and this is they specify that they are using phenolic, glycosides and carboxylic esters.

[25:23]

So that is what they're considering for bound salicylates. Basically, we don't really know what the difference between them, it's difference between them in the body, like, you know, I kind of think about, like, if you're a single person, or if you're married, right, as a single person, you can certainly go around and travel, you know, easily, and it's easier to get one ticket, and it's easier to, you know, navigate as a single person, where if you're married, or if you're taking a family of five, right, it's going to be harder for you to navigate. So, you know, you can kind of think about it like that. You know, one thing that we don't know is how long it takes for these bound salicylates to break down in the body. Like it could take, let's say, one to three days. I'm not saying I know that for sure. I'm just saying, what if, if that were the case, then maybe the bucket theory isn't true. And maybe it's just bound salicylates that are taking a long time to unravel and your body are, you know, are causing problems later on in the day or a couple of days rather than like a dose theory. So that could possibly be a problem. We don't know very much about so, well I should say we don't know very much about it, as far as what happens in the body. So, I picked out a bound salicylate. So, this is a compound from willow bark and Populus, salicin comes from the Salicaceae Family. It's actually a plant that I study, oddly enough. And salicin here, you can see that on the left, I showed you the salicin alcohol, which is the base molecule. You can kind of see here where you can pick it out. And then the other portion, all these OHs, and it is a ring of carbons with an oxygen. I don't know if that is an aromatic or not. I didn't do the, you know, see if it fits the test criteria. But you have all of these OHs on there. This is actually a sugar molecule. This is glucose. I think it's D-glucose specifically. But it's just a certain shape of sugar. So that is a sugar molecule attached to a salicyl alcohol. Now this one here probably, even though it's bound, it actually probably digests very quickly in the body because sugar is very water-soluble. So, it's possible that this is something that breaks up quickly. I'm not sure what that area where the O is how easily that breaks up. But I do know that people use willow bark for medicine. So, I'm guessing you can't take too long to digest in the body. So anyways, so that is what a bound salicylate looks like compared to an unbound. And of course, I will as I learn more about these, I will obviously do a video on these in the future. Maybe I'll pull up like, you know 10 different examples of bound salicylates and we can look at them in a little bit more detail. Alright, and now the test. You win regardless if you get the answers right, especially if you're still here. The first one that gets brought up a lot is whether or not nitrates or nitrites are salicylates? Now, I am in no way saying that they are healthy for you. They can both be a synthetic compound or in, you know, a natural compound. Celery is a great example of natural nitrates. Bacon, usually in order to cure meats we add these molecules and you can actually be sensitive to nitrates and nitrites. If you're already salicylate sensitive, and let's say you know gluten intolerant, it's not terribly unlikely that these might cause you problems. It's possible but we're looking at a salicylate viewpoint only. So, let's look at the two that I pulled up. I have NO2- and NO3- and these here nitrate and nitrate, I did those backwards on the so these two, these form ionic bonds. And so, they also don't have carbon. So, in these cases, these are not organic compounds, because they don't have carbon and they're not covalently bonded.

[30:18]

So, in those cases, these are inorganic compounds, meaning that these are not at all anywhere close to a salicylate. And also, you can just look at them, there's no benzene ring in there. So, we don't even need it. We don't even need to blink twice. Just because I said it's an inorganic compound does not mean that it does not occur naturally in nature. Again, the celery is an example of that. This is one that I get often oxalates because anybody that explores salicylates sensitivity probably also explores amine or oxalate sensitivity, and oxalates are in coffee, decaf coffee, they're in chocolate. There's a lot of actually a lot of foods that I eat, and everybody asked me if I'm oxalate sensitive, or if I watched that I do not, I do not react to them at all. Now, here are some diagrams of oxalates. You can see they have carbons got their carbon backbone, right, they've got two carbons in there. In some cases, you might have a ring there. I don't know if that's an aromatic ring or not. But there is a ring of carbons and oxygens and magnesium and calcium and different things. But basically, when I look at these, I say okay, they are in an organic compound, check. They are also containing carbons, check. But I don't see any phenols in here, any benzene rings and so this here cannot be a salicylate. This is one that gets asked often citric acid or ascorbic acid. Now, there is the possibility that these are derived naturally. You can see that this picture here even puts a lemon on there. We know lemons are high in salicylate. So, it's possible if it is not refined enough that it could have some natural botanicals in there. And those could contain salicylates. Citric acid and ascorbic acid are usually so refined and even RPAH say that they're fine. In its purest form, they are not a source like you can look at it, obviously, we've checked our boxes here, we've got carbons, plenty of carbons in there, check we've got which means it's organic. We have no benzene ring in citric acid, you know, looks like it could be close, but it's not. And then also for ascorbic acid, you have a ring there, but it's a five-sided ring with an oxygen in it. So pretty far away from a benzene ring. So, these here are not a salicylate in any way, shape, or form. This is another one that people ask about is magnesium stearate. It's available, they use it a lot in supplements. I don't know what the purpose of it is in supplement, I feel like maybe an anti-caking agent it oddly enough magnesium and calcium stearate are soap scum. So, you know super fun, you can do whatever you want with that, but in small amounts is supposed to be well tolerated. So here, this one is kind of funny, weirdly represented, but you've got the magnesium there on the left. And then you have your two oxygens with your minus so those little two plus and those little oxygen minuses those are going to hook up and essentially marry each other. And then you have these long chains of carbon and really nothing else on there. So, these here, there is no benzene ring on here. Yes, it is an organic compound. But no, it is nothing like a salicylate. Alright, I'm moving on to tricky things. So here are two compounds. These look super tricky. They have a benzene ring. And they also have a phenol on there because they have the O H. Now, I'm not entirely sure what this other O H does to make it not a salicylate or dangerous for us. But we have these are not salicylate. I'll show you what they are. The one on the left is dopamine and the one on the right is an adrenaline noradrenaline or norepinephrine. These here both are manufactured or created by your body naturally and they are needed for everything that you do. So, they look kind of shady with the tools that we have, but they are safe. Of course, I don't recommend too much adrenaline at any one point in time, obviously, you can get really sick if you have too much adrenaline, so, but I'm just saying it's not a salicylate, but it kind of looks like one.

[35:10]

Alright, moving on this one, it comes up a lot. And this is kind of, I think, kind of that idea you're allergic to phenols. But this one, these are benzoates or benzoic acid, there's sodium benzoate is another one. But the one, basically, you've got a benzene ring, and that acid on there. And that is possibly something that could make you sick, but it is not a salicylate. I'm not saying that it can't you know, the thing about salicylate is that it unlocks a key in your body, like it functions of the key and unlock something your body so that you have a reaction. I'm not saying that benzoates or benzoic acid can't do that. But, you know, it really needs another oxygen on there in order to, you know, be a salicylate, but it's pretty close. So, with that one, I'm going to say, I don't know, I can tell you it is not a salicylate, it is treated differently, as benzoates,  it could be something that could cause you problems. So, you know, keep an eye out for that if you get something like a medicine or I see them in cosmetic sometimes - benzoates. So, I would I'm still experimenting with these, I had some food products that use it as a preservative. And I haven't had any issues with it, but doesn't mean that you might not. And then let's look at a couple of dyes. So, a lot of people are concerned about dyes, both naturally occurring or synthetic. I like to make eyeshadow and makeups and different things like that. And so, I wanted to look up some of the colorants that I use. So, these here, the ones on top, we've got manganese violet, you can see that there is manganese on the left, you've got your I think those are phosphorus, the Ps. And then you have your some kind of like ammonium group. But you've got all of these things here. These, none of these have a carbon in them. They use ionic bonding, which is why they have a little plus and stuff. There's no carbon in here. There's no covalent bonding, there's no benzene ring, there's no chance that this is a salicylate. So, if you found a makeup that you liked, but it had this in it, this should probably be okay for you. Here is iron oxide, iron three oxide and iron two oxide. These are basically just iron with oxygens. So that's the little Fe symbolizes iron, you've got your oxygens there, you've got double bonds, single bonds, and these again, are nothing close to a salicylate. This one here, I thought I'd throw it in there because it came up with colorings and dyes and people use curcumin for dyeing things yellow. Now, Curcumin is from turmeric, but turmeric is not this compound only. This is the active ingredient in turmeric. So here, you can see that there are two very questionable compounds in here. And these look like salicylates to me. I'm going to have to break it down just a little bit more. I'm not sure what that oxygen with a carbon on the end, what it can look like. But this could very well be an example of a bound salicylates. You've got this molecule in the middle. And then you've got these two phenols on the end that look a lot like salicylates and this very well could just be bound to conversion. Now, we know from former studies that they show up very high just Malakar study at 30.83 milligrams per kilogram is very high. This is for turmeric, this isn't for curcumin, but still in the very high category. Alright, that's all I've got for today. Let me know. I'm afraid to say let me know if you have any questions down below. I will try to answer them the best that I can. But basically, I just want you guys to feel a little bit empowered that you can look up a molecule on ChemSpider and have an idea for yes, this is absolutely not salicylate. And this here looks questionable. I'm going to be a little bit more cautious on that. So, I wish you the very best thanks so much for sticking it out to the very end. I really hope that this information was helpful, and maybe even liberating, and I wish you the very best a viewer at low salicylate journey, if you found this content valuable don't forget to like and subscribe. And also, you can find me on Instagram at Low-Sal-Life. Alright, take care. Bye.